Table 5 The Leeds Sleep Evaluation Questionnaire (LSEQ) Results

Overall Score

Washout

2.91 ± 0.13

2.84 ± 0.13^abc

^a 0.0129

Week 2

3.02 ± 0.13

3.08 ± 0.13^b

^b 0.0280

Week 3

3.09 ± 0.13^a

3.10 ± 0.13^c

^c 0.0129

placebo

treatment

Sleep Quality (wakefulness)

Washout

2.86 ± 0.20

2.73 ± 0.20^abc

^a 0.0054

Week 2

3.03 ± 0.20

3.16 ± 0.20^c

^b 0.0249

Week 3

3.16 ± 0.20^b

3.23 ± 0.20^a

^c 0.0249

placebo

treatment

Difficulty Falling Asleep

Washout

2.90 ± 0.24^a

2.83 ± 0.24^bc

^a 0.0469

Week 2

3.20 ± 0.24

3.30 ± 0.24^b

^b 0.0469

Week 3

3.16 ± 0.24

3.36 ± 0.24^ac

^c 0.0139

placebo

treatment

How Quickly Fall Asleep

Washout

2.87 ± 0.24

2.84 ± 0.24

ns

Week 2

3.14 ± 0.24

3.27 ± 0.24

Week 3

3.24 ± 0.24

3.27 ± 0.24

placebo

treatment

Sleepy Before Bed

Washout

3.15 ± 0.22

2.92 ± 0.22^a

^a 0.0237

Week 2

3.15 ± 0.22

3.29 ± 0.22

Week 3

3.25 ± 0.22

3.39 ± 0.22^a

placebo

treatment

Restless During Sleep

Washout

2.80 ± 0.23^a

2.83 ± 0.23^b

^a 0.0190

Week 2

3.00 ± 0.23

2.93 ± 0.23

^b 0.0357

Week 3

3.30 ± 0.23^ab

3.13 ± 0.23

placebo

treatment

How Difficult to Wake Up

Washout

2.93 ± 0.22

2.86 ± 0.22

ns

Week 2

3.03 ± 0.22

2.90 ± 0.22

Week 3

2.96 ± 0.22

2.90 ± 0.22

placebo

treatment

How You Feel When You Wake Up

Washout

2.78 ± 0.24

2.72 ± 0.24

ns

Week 2

2.98 ± 0.24

3.02 ± 0.24

Week 3

2.92 ± 0.24

2.95 ± 0.24

placebo

treatment

How Long to Wake Up

Washout

2.97 ± 0.16

2.90 ± 0.16

ns

Week 2

2.83 ± 0.16

3.03 ± 0.16

Week 3

2.83 ± 0.16

2.97 ± 0.16

placebo

treatment

Balance/Coordination Upon Waking

Washout

3.00 ± 0.12

2.93 ± 0.12

ns

Week 2

3.03 ± 0.12

3.03 ± 0.12

Week 3

3.13 ± 0.12

3.00 ± 0.12